Detroit Symphony mus
Detroit Symphony musicians strike http://htxt.it/5YKS
Thoughts on science and socialism
evidence that rhesus monkeys pass the mirror-test for self recognition? (Also a test of hellotxt) http://htxt.it/siKE
From the WSWS:http://www.wsws.org/articles/2007/mar2007/dawk-m15.shtml
From the WSWS, For the full article, click here.
I have been reading Chetverikov's 1926 essay "On Certain Aspects of the Evolutionary Process from the Standpoint of Modern Genetics." I am posting my notes on the essay here, since I think his work would be well worth disseminating, as part of a broader study of the contribution of Soviet geneticists of the 1920s to the great evolutionary synthesis. I will comment more on his work in future posts. These are mainly excerpts from what I take to be the most important sections.
Sergei Sergeevich Chetverikov (1880-1959) was one of the first theoreticians of the evolutionary synthesis, a scientific movement that sought to place evolutionary theory firmly within the framework of modern genetic theory. He was apparently involved in anti-government activity as a student in Moscow around the time of the revolution of 1905. He was arrested at one point during this period. He was arrested and banished from Moscow in 1929, during the early period of Stalinist repression, perhaps for being involved in an exclusive genetics discussion group, being opposed to the theory of the inheritance of acquired characteristics, or after being denounced to the political police by one of his students. His work on genetics ended conclusively in 1948 with the rise of Lysenkoism. Chetverikov had a profound impact on other thinkers of the synthesis, particularly Ernst Mayr. In addition to theoretical work, he conducted important studies of the genetics of Drosophila melanogaster, the fruit fly, building on the research of Morgan. He used an inbreeding technique to reveal recessive alleles.
The basic question of the evolutionary synthesis, as formulated by Chetverikov: “How can one link evolution with genetics, and bring our current genetic notions and concepts within the range of those ideas which encompass this basic biological problem? Would it be possible to approach the question of variability, the struggle for existence, selection, in other words, Darwinism, starting not from those completely amorphous, indistinct, indefinite opinions on heredity which existed at the time of Darwin and his immediate followers, but from the firm laws of genetics?”
1. The Origins of Mutations in Nature
Problem of the relative absence of mutations in nature, compared to the number of mutations observed during the course of laboratory work.
Genetics is the basis for speciation and evolution. It is not simply a purifying mechanism, in which some basic species substance is conserved throughout all time. “We have already seen in several examples mentioned above that mutational variability touches upon various characters greatly different in significance. Alongside of the least salient traits, such as the color of the body, such important characters of Drosophila are changed as venation, wing structure, etc., which are fundamental in the modern systematics of insects for distinguishing the higher systematic categories. Consequently, it is necessary to acknowledge as completely erroneous the idea which some express, that mutations deal in only a superficial way with species traits, being characteristic of differences between varieties, while, apart from these small aberrations, there is a ‘basic substance’ of organisms which is not subject to mutational changes. Because of this, it is argued, the process of evolution, the process of the transformation of whole organisms into others, could not be achieved by means of mutations. Speaking figuratively, it is claimed that with all mutations, a fly always remains a fly, and a rat a rat, and never does the latter produce deviation in the direction of a rabbit or a dog.
“But here two concepts are confused: the diversity of characters subject to genotypic variability, and the scope of variability, i.e., the amplitude of deviation. Actually, we see that absolutely all parts of the organism are subject to genotypic variation. But, although genotypic variability is discontinuous, its leaps, naturally, cannot be infinitely large, so that the amplitude of aberration is limited, and the limit is determined by the structure of the genes themselves. Abrupt and profound changes of the organism are possible only be means of a prolonged accumulation of mutational changes, of long-termed stratification of one deviation upon another.”
2. Mutations under conditions of free crossing
Formulation of the biological species concept. “The definition of species, as an aggregate of individuals constituting a single freely intercrossing complex…” That is, a species is a unity of difference. Morphological difference by itself does not imply the existence of two species. “And from our genetic experiments on the most diverse animal and plant organisms, we now known that it is possible to create two groups of such organisms, which will differ from each other by a perfectly concrete complex (theoretically speaking, as large as one wishes) of morphological characteristics, which are not connected by intermediate forms; that is, having a so-called morphological hiatus, but at the same time belonging genetically to the same species.” Incidentally, this highlights the difficulties associated with determining species structure when looking at fossil material.
Variation is essential to the species concept, and is necessary for the operation of natural selection. But how is variation maintained? Objections were raised to Darwin’s theory from an engineer, Professor Jenkins, that the free crossing of individuals (under the assumption of blended inheritance) would quickly dissolve any new deviation. Led Darwin to move away from hard inheritance in explaining the persistence of variation, to Lamarkian theories. A.R. Wallace refers to “the swamping affects of intercrossing.” To truly understand variation and the maintenance of variation, we need genetics.
Hardy’s law of equilibrium under free crossing. “the relative frequencies of homozygous (dominant as well as recessive) and heterozygous individuals, under conditions of free crossing and in the absence of any kind of selection, remain constant, provided that the product of the frequencies of homozygous individuals (dominant and recessive) is equal to the square of half of the frequency of heterozygous forms.” pr = q2. “Since for any value of p and r a value of 2q may be found to satisfy the equation…a freely crossing population may be in a state of equilibrium with any proportions of homozygous dominant and recessive forms.”
Law of stabilizing crossing (Pearson’s law): “under conditions of free crossing with any initial ratio of frequencies of homozygous and heterozygous parental forms, a state of equilibrium will be established in the population as a consequence f the very first generation of free crossing. Thus, should a state of equilibrium in a freely crossing population be disturbed from without, as a result of the very first subsequent crossing, which we will call stabilizing crossing, a new state of equilibrium is established within the population, at which the given population will remain until some new external force removes it from this state.” Among these external forces, we may include selection and mutation.
These laws imply that mutations may appear and then subsist in a population in heterozygous form, only rarely being expressed phenotypically. “A species, like a sponge, soaks up heterozygous mutations, while remaining from first to last externally (phenotypically) homogeneous.” “The older the species, the more mutations are accumulated within it, the more frequently is one or another of them disclosed in the homozygous state, and the more the species becomes externally genetically variable. Generally speaking, all other conditions being equal, genotypic variability of a species increases proportionally to its age.”
The smaller the population size, the greater the probability that absorbed mutations will express themselves phenotypically. Basis for a theory of speciation based on isolation, which foreshadows Mayr’s work. “If we imagine that the total number of individuals of a given species N, is subdivided into a series of isolated colonies, then the frequency of origin of new mutations within the limits of the entire species will not suffer, but the probability of reappearance of each such mutation will be once more considerably increased, depending on the reduced size (n) of the colony, within which it originally arose. Thus, we approach a more profound understanding of the enormous role which the factor of isolation plays in the origin of species variability…A species, as we have tried to show above, represents limitless diversity of genotypic combinations, and each isolation creates in it at once the exceptionally favorable conditions for the manifestation of heritable variations...And so, isolation, under the conditions of a process of continuous accumulation of mutations becomes, by itself, a cause of intraspecific (and consequently, interspecific) differentiation. Of all the factors contributing to the break-up of a species into separate non-interbreeding colonies, it is necessary, naturally, to put spatial, geographical isolation in the first place as the most powerful and common factor of intraspecific differentiation.” Also, isolation in time (different mating cycles), or ecological isolation. Isolation at the margin of a population, where the struggle for existence is more intense.
3. Natural selection
Free crossing vs. natural selection: “In the foregoing analysis of free crossing, we tried to establish its role as a factor stabilizing a given population. In its very essence it is a conservative factor, preserving the genotypic composition of the species in the condition in which it is found at a given moment. Natural selection (and, in general, selection in any form) is, in this connection, its direct antagonist. If free crossing stabilizes the population, then selection, on the contrary, all the time displaces the equilibrium state, and, if in this sense we may call free crossing a conservative principle, then selection, undoubtedly, is the dynamic principle, leading ceaselessly to modification of the species.”
Intensity of selection. Difference in the mechanics of allele distribution for recessive and dominant traits. A mutation that is beneficial will rapidly spread in its initial phases if it is dominant, but it takes longer to eliminate the less beneficial allele after the dominant allele has spread through much of the population (since selection will have a difficult time acting on the recessive, less beneficial allele, when there is a low probability that it is expressed phenotypically). On the other hand, a mutation that is beneficial but recessive, will take a long time to spread during the initial phases, but will proceed much more rapidly once it has spread to a substantial section of the population. This is because during the initial phases, it will only very rarely be expressed in the phenotype of an organism. However, even a trait that has only a small benefit will tend to spread throughout the entire population after sufficient generations. New mutations will not be lost after one generation.
Another conclusion: “transformation change of a freely crossing population—species, the replacement of the less adapted form by the more adapted one, in a word, the process of adaptive evolution of the species, always proceeds to the end… This conclusion is very important for an accurate understanding of the role of various features in the evolutionary process. Under conditions of free crossing, that is, until there is isolation…the struggle for existence and natural selection can continuously alter the physiognomy of the species, can disseminate more and more new adaptive characters through the whole mass of individuals of the species, can perfect any features of its organization, but never under these conditions does the species give rise to a new species, never will there be a subdivision of the species into two, never will speciation occur.” If selection should cease to operate on the trait while the process is not complete, this will result in stable polymorphism.
“We noted above that the role of free crossing in the process of evolution is a conservative one, striving to maintain the status quo, whereas natural selection acts as an opposing, dynamic factor. But if we bring into the scope of our analysis the process of continuous origin of new mutations as well, then this concept needs to be both changed and supplemented. While free crossing, storing and preserving within the species all the newly arising mutations, gradually unfixes the characteristics of the species, makes it less stable, and produces intraspecific differentiation, natural selection, on the contrary, preserves the stability of the species, its monomorphism. Removing and gradually eliminating all mutations, which in the last analysis appear to be harmful, natural selection purifies the species of contamination by accumulated variations, and, in the case of favorable changes, spreads them to all the individuals of the species, thereby reimposing on it homogeneity.”
On “adaptationism”. “Systematics knows thousands of examples where the species are distinguished not by adaptive but rather by neutral (in the biological sense) characters, and to try to ascribe adaptive significance to all of them is work which is as little productive as it is unrewarding, and in which one does not know at times whether to be more surprised by the boundless ingenuity of the authors themselves or by their faith in the limitless naïveté of their readers.”
“Not selection, but isolation is the actual source, the real cause of the origin of species.”
“Finally, even in those cases in which we are in a position to establish the presence of truly adaptive differences between species, genera, etc., it is necessary to be very cautious in accepting the idea that these differences are of a primary character, i.e., in recognizing that precisely they have given rise to a splitting up of the initial single form into two, thus leading to the process of speciation. It should not be forgotten that, as we just saw, every species in the course of its existence obligately undergoes as a whole Waagen’s adaptive mutation, should a favorable mutation, in our sense, arise, and thereby acquires an adaptive trait absent in its kin. A new species-distinguishing adaptive trait is established, but it is not the cause of the splitting-up of close forms, but on the contrary, its species-characteristic nature is a result of still earlier inter-specific differentiation.”
4. Genotypic milieu
Unity of the genotype, Genotypic milieu, pleiotropy. “The concept of pleiotropic action of genes consists of the idea that every gene may influence not only the specific character corresponding to it, but a whole series of others; generally speaking, the entire soma. In so far as we now accept the proven localization of genes in the chromosomes, and in so far as all cells of the body receive the full set of chromosomes, so in the ultimate differentiation of the cells determining some specific trait all genes can be influential, affecting by their action one or another form of manifestation of genes specifically corresponding to a trait.
“In this way, the former notion of the mosaic structure of the organism consisting of various, independent characters, conditioned by various, independent genes, is discarded. The genes remain pure and qualitatively independent of each other, but their manifestation, that is, the traits they condition, are now a complex result of the manifold interaction of all the genes comprising the genotype of the organism. And each individual is in the literal sense an “in-dividuum”—not divisible. It is not divisible not only in its soma, not only in the physiological functioning of its various parts, but indivisible in the manifestation of its genotype, its hereditary structure. Each inherited trait, the hereditary structure of each cell of its body, is determined by not just some one gene, but by their aggregate, their complex. True, every gene has a specific manifestation, its “trait.” But in its expression this trait depends on the action of the whole genotype.
“Each gene does not act isolatedly from the whole genotype, is not independent of it, but acts, manifests itself, within it, in relation to it. The very same gene will manifest itself differently, depending on the complex of other genes in which it finds itself. For it, this complex, this genotype, will be the genotypic milieu, within the surroundings of which it will be externally manifested.”
The Republican War on Science by Chris Mooney, Basic Books, New York, 2005, 351 pp., US$24.95, CAN$34.95
There have been a number of books written in the past few years that deal with different aspects of the attack on science. Some of these are useful, bringing together certain material about the attempts by corporations and political organizations to undermine scientific conclusions. But most fail to make a serious analysis of what lies behind the attack on science.
Chris Mooney’s book, The Republican War on Science, falls clearly within this category. Mooney is a journalist who has written on scientific issues for publications such as Mother Jones, American Prospect and the Washington Post.
The fundamental flaw of his book is indicated by the title. Mooney sees the war on science, in the end, as simply the product of bad politicians—Republicans—who have to be reined in—by the Democrats. Such an approach, almost by definition, skirts over the more profound social and historical roots of the attack on science, as well as the Democratic Party’s own role in facilitating it.
***
There are deeper roots to the attack on science that Mooney misses entirely. The rise of modern science during the Renaissance and Enlightenment period was intimately bound up with the rise of the bourgeoisie as a dominant social class in Europe. In its struggle with the old feudal classes, which were generally allied with the Catholic Church and its promotion of religious dogma, the rising capitalist class took up the banner of rationality, knowledge and science.
The development of science was necessary for the development of the means of production, including the introduction of new technologies and new forms of communication and transportation. These advances strengthened the hand of the bourgeoisie and increased its economic power relative to the landed nobility. The bourgeoisie was at that time a progressive class, in the sense that its own interests as a class corresponded with the development of the productive forces.
What has happened since that time, so that the same backward—as Mooney notes, pre-Enlightenment—conceptions that were once the purview of the feudal aristocracy are now championed by the president of the United States, the head of state at the center of world capitalism? The answer lies in the changing relationship of the bourgeoisie to society as a whole: from a progressive and revolutionary class, it has become the principal force of reaction—the main barrier to the further development of the productive forces and defender of a historically outmoded socio-economic system.
Of course, this is not a new situation. The historical bankruptcy of capitalism has been long in the making. Backwardness is hardly a monopoly of the US government. One need only recall the barbarism of the fascist movements of the last century.
At the same time, it is not accidental that the anti-rationalist conceptions that animated these movements share common features with those that form the bedrock of the Bush administration. The attack on science and rationality is characteristic of a society in mortal crisis.
This does not negate that fact that over the past several decades there have been immense technological advances, centered on the development of computer technology. There are certainly sections of the ruling class in the United States that are concerned about the consequences that the anti-scientific conceptions promoted by Christian fundamentalists and their allies have for the skill level of American workers and the general ability of American firms to compete on the world market. There is also concern that the major scientific advances, such as those associated with stem cell research, will be made in countries that compete with US capitalism.
However, the general relationship of the American ruling class to the development of the productive forces is an antagonistic one. The growth of these forces brings with it not a strengthening of its position, but rather an intensification of the contradictions of American and world capitalism—above all the contradiction between globalized production and the nation-state system, and between the social character of production and the private ownership of the means of production.
At the same time, the expansion of scientific knowledge to broad sections of the population can only serve to intensify opposition to imperialism’s promotion of militarism and social reaction. If during the period of the great bourgeois revolutions reason was a tool to be used against feudalism, it now facilitates the struggle against capitalism.
In a fundamental sense, the American ruling class is in conflict with truth. A figure such as Benjamin Franklin—who engaged not only in revolutionary politics, but also groundbreaking scientific research—represented that which was progressive in the emerging American bourgeoisie. Today, the American ruling class is aptly represented by a George Bush, who combines social reaction with intellectual poverty and cultural backwardness.
The inability of Mooney and similar writers to examine the deeper historical issues behind the attack on science reflects a definite political outlook. Ultimately, Mooney’s hope is that all the problems he outlines can be solved through support for the Democratic Party or even more moderate Republicans. He concludes his book by declaring that “we face a political problem, one that requires explicitly political solutions,” and calls for the American people to vote “today’s Right” out of office.
Mayr’s book Toward a New Philosophy of Biology is filled with truly profound and fascinating essays. In “Cause and Effect in Biology,” he discusses the question of determinism and prediction in biology. The question is quite important, because a mechanistic interpretation of the physical world, which considers only physical or physicochemical causes and explanations, fails to really account for biological phenomenon (and other, higher, levels of organization, including social development). This leads generally to supernatural explanations for life—vitalism, spiritualism, religion, etc.
In the works of Descartes, one finds this relationship—between mechanistic materialism and spiritualism—expressed quite clearly. The body is a machine, according to Descartes, something akin to a system of water pumps. This obviously fails to account for the great complexity of biological phenomena, particularly mental experience, and the soul is postulated to account for what can not be explained by analogy to a simple machine. And the mechanistic worldview of Newtonian physics (or rather, the attempt to explain all of the material world in reference only to this physics) is in fact quite compatible with the most varied forms of religious obscurantism, and Newton himself embodied these two ways of seeing the world (he devoted as much time to Biblical exegesis as he did to the creation of the new physics).
Mayr quotes C. Bernard as declaring, “We admit that the life phenomena are attached to physicochemical manifestations, but it is true that the essential is not explained thereby; for no fortuitous coming together of physicochemical phenomena constructs each organism after a plan and a fixed design (which are foreseen in advance) and arouses the admirable subordination and harmonious agreement of the acts of life…Determinism can never be [anything] but physiochemical determinism. The vital force and life belong to the metaphysical world.” Indeed, to a certain extent this argument is cogent, i.e., if you accept the premises, then the conclusion more or less follows. However, the question is really whether or not physiochemical determinism accounts for the entire scope of natural law governed processes. Similar arguments are brought out by those who would seek to deny that there is a science of history—history can not be a science because it cannot have the sort of laws that physics has. Popper has made a variety of this argument in some of his writings. The social analogy of vitalism, the idea that there is a special “life force,” generally associated with the soul or some metaphysical entity, has its analogies in the historical sciences—the “great man theory of history,” and other varieties of historical idealism.
Indeed, the relationship between biology and the science of human history is deeper. Biology is a historical science. As the great evolutionist Dobzhansky reminded us, “nothing in biology makes sense outside of evolution,” that is, outside of history. The rise and triumph of evolutionary biology, beginning with Darwin and becoming firmly established during the first decades of the twentieth century with the “evolutionary synthesis,” revolutionized biology, placing evolution at its core and requiring all biological phenomena to be understood in the process of their historical development.
Mayr quotes the physicist Max Delbruck (“A physicist looks at biology,” 1949): “Any living cell carries with it the experiences of a billion years of experimentation by its ancestors.” That is, the biological entity—the cell, the organism, the species—is the product of a prolonged period of interaction between its ancestors and the surrounding world. To understand the entity, one must understand how it came to be, how its ancestors interacted and adapted to the totality of its organic and inorganic environment. For the purposes of categorization and experimentation, it can be abstracted from its historical and biological environment, but a truly concrete understanding of its nature comes only from cognition of this environment. Speaking more generally, Hegel once said that if one were to eliminate one speck of dust, the entire universe would collapse, by which he meant that the universe can only truly be comprehended as a unity of difference, and not as isolated essences.
In discussing cause and effect in biology Mayr distinguishes between two fundamental types of cause: proximate cause and ultimate cause. Among the proximate causes, one includes the physiochemical or immediate environmental factors that produce a biological event, e.g., the migration of a bird on a particular day. One might point to the temperature on that day, a certain neural state induced by the environment in the bird, etc. When one begins to explain the event in terms of the evolutionary heritage of the bird, its specific adaptations that have led it to migrate south when the weather turns cold, etc., then one is dealing with ultimate causes. “These are causes that have a history,” Mayr writes, “and that have been incorporated into the system through many thousands of generations of natural selection…[P]roximate causes govern the responses of the individual (and his organs) to immediate factors of the environment, while ultimate causes are responsible for the evolution of the particular DNA program of information with which every individual of every species is endowed.” The “purposiveness” of biological phenomena, which so impressed Bernard, is a product of these historical, ultimate causes.
In history, the proximate causes are those that deal with the particular individuals or political forces acting at a given stage of history—the assassination of the Archduke let the Austrian government to issue an ultimatum, sparking a network of alliances that led to World War I. The ultimate causes are those that refer to the deeper social forces at work—the rise of German imperialism, the conflict between the nation-state system of
We come now to the problem of prediction in biology. According to Mayr, “The theory of natural selection can describe and explain phenomena with considerable precision, but it cannot make reliable predictions, except through such trivial and meaningless circular statements, as, for instance: ‘The fitter individuals will on average leave more offspring.’” While there are many types of biological predictions that can be made, “Probably nothing in biology is less predictable than the future course of evolution.”
It is worthwhile examining in some detail the four reasons that Mayr cites for the difficulty of biological prediction, because an important question that a Marxist would want to address is how a science of human history may have predictive power. It is one thing to explain something scientifically; it is another to be able to predict the future course of events. The first reason he gives is the “randomness of an event with respect to the significance of the event.” In particular, DNA mutations are random: “The occurrence of a given mutation is in no way related to the evolutionary needs of the particular organism or of the population to which it belongs.” Similarly with recombination. Second, “Uniqueness of all entities at the higher levels of biological integration.” Third, “extreme complexity.” And fourth, “Emergence of new qualities at higher levels of integration.”
I am not sure I see a problem with the latter three reasons. Mayr himself points out that the uniqueness of individuals still allows for statistical predictions, and draws an analogy to particles in a gas moving individually in different and unpredictable directions, but having predictable effects at a more macroscopic level. Moreover, extremely complex entities do not necessarily preclude predictability. Bring a fire to a man’s hand and he will withdraw it, regardless of how complex his biological constitution may be. One can predict the stages through which a man will pass in his biological development as well, because this extremely complex development is nevertheless regulated by genetic mechanisms. Finally, certainly with complex entities one sees the emergence of new characteristics, however one also sees the emergence of new laws, of new regularities, which allow predictions at the higher level of organization.
It seems to me that the first reason is the most significant. Evolution involves a large degree of randomness, and there is no direct relationship between the “evolutionary needs” of a population with this randomness. However, I am not convinced that this really eliminates the ability to make predictions about evolution either. Can one not predict that if one introduces a species of bird into an environment in which the only source of food favors birds with larger beaks, that the population of birds will evolve toward larger beaks? One knows that there is variation in beak size and this is governed by different allele frequencies. The larger beaks will tend to be selected for. Of course, the prediction is highly conditional—assuming that the birds do not find a different source of food; assuming that a mutation is not introduced that sends the population in a different evolutionary direction; etc. Nevertheless, randomness in mutation and recombination does not do away entirely with the ability to make predictions.
How to bring this discussion to the question of historical laws and historical predictions? While I have argued that predictions about biological evolution are still possible, I think the case can be made more strongly for social development, which involves very different forms of organization than biological evolution. Human societies are highly regulated in a way that biological populations in general are not, and this introduced very definite “evolutionary pressures” and much more predictable responses to these pressures. In particular, the process of production and the growth of the productive forces replaces evolution as the main driving force of the development of the human species [though of course biological evolution has not disappeared].
As Marx wrote, “In the social production of their existence, men inevitable enter into definite relations, which are independent of their will, namely relations of production appropriate to a given stage in the development of their material forces of production…The mode of production of material life conditions the general process of social, political and intellectual life…At a certain stage of development, the material productive forces of society come into conflict with the existing relations of production,” which begins an era of social revolution. “In studying such transformations it is always necessary to distinguish between the material transformation of the economic conditions of production, which can be determined with the precision of natural science, and the legal, political, religious, artistic or philosophic—in short, ideological forms in which men become conscious of this conflict and fight it out.”
There is no real correlate to class structure at a biological level. One sees for the first time in the history of life on earth the emergence of a dynamic social structure that, through culture (by which I mean the use of tools and knowledge and language that is transmitted from generation to generation outside of the framework of the genome), comes to dominate historical change within the population. The social requirements for the continued development of the productive forces and human society are much more definite than the evolutionary requirements for the continued development of populations in general. This is because the development of the productive forces imposes definite constraints on the social relations that will allow for their further development. For example, the socialization of the production under capitalism can only be continued and developed through the abolition of the private ownership of the productive forces. The internationalization of the productive forces can only be further developed through the abolition of the system of competing nation-states. In this sense one can predict the necessary stages in the development of human society, the “material transformation of the economic conditions of production…can be determined with the precision of natural science.” [In the comments section of this post, I elaborate on the issues raised in this paragraph. I have also changed above the phrase "socialization of the productive forces" to "socialization of production."]
I would also make the argument that the “selection pressures” imposed by the requirements of the productive forces produce the required “mutations”, or individual actions and persons, with far greater regularity than evolutionary requirements produce the needed mutations in DNA. The required personalities and political tendencies are more or less direct products of the social environment, though “more or less” here encompasses a great deal, since the relationship between the material base of human society and ideological manifestations is a complex one. However, this relationship allows for a sort of Lamarkian, or non-genetic evolution of human society, thereby reducing the amount of randomness. In human history, and not in biological evolution, the need for birds with bigger beaks actually leads to the production of birds with bigger beaks.
This by no means diminishes the need for conscious action among men, for all changes in the social relations of production must be mediated through these conscious actions. The role of the subjective factor in the conflict between different social forces requires that any definite predictions be conditional upon decisions and actions made by individuals and by parties. One can predict with absolute certainty the emergence in the coming period of enormous social struggles on an international scale; one can say with certainty that the crisis of world capitalism and the further development of the productive forces can only be resolved through an international socialist movement. However, the result of these struggles and the success of this movement is an open question that remains to be decided.
In his book, Toward a New Philosophy of Biology, Ernst Mayr has an essay entitled “The Unity of the Genotype” that is well worth examining. He summarizes the views of a theoretical lineage (beginning with the Soviet philosopher Chetverikov in 1926) through Mayr himself as follows: “Free variability is found only in a limited portion of the genotype. Most genes are tied together into balanced complexes that resist change. The fitness of genes tied up in these complexes is determined far more by the fitness of the complex as a whole than by any functional qualities of the individual genes.” This view must be counterpoised with the Mendelian conception, which it seems to me finds its most modern expression in the writings of Richard Dawkins, of the independence, the segregation, of genes. Here the gene (however this may be defined, a tricky matter) is treated as an isolated unit, the ultimate unit of selection. Evolution is understood as the changing of gene frequencies in a population.
In contrast, Mayr argues that it is necessary to treat the entire genotype as a unified complex of interacting parts. He traces this back to Darwin’s concept of correlation of growth, formulated in the Origin of Species, as the observation “that the whole organization is so tied together during its growth and development, that when slight variations in any part occur, and are accumulated through natural selection, other parts become modified.” Mayr brings in several different manifestations of the cohesion of the genotype, including Lerner’s concept of genetic homeostasis, the tendency for a population to loose some or most of an artificially selected trait when the selection pressure is removed; and the often-observed narrowness of hybrid zones, in which gene flow between two species that have come into contact with each other does not extend beyond a narrow band surrounding the area of cross-mating.
He draws the following conclusions from these observations: “(1) Since the fitness of a gene depends in part on the success of its interaction with its genetic background, it is no longer possible to assign an absolute selective value to a gene. A gene has potentially as many selective values as it has possible genetic backgrounds; (2) The target of selection does not consist of single genes but rather of such components of the phenotype as the eye, the legs, the flower, the thermo-regulatory or photo-synthetic apparatus, etc. …”
The concept of the cohesion of the genotype is useful, because it helps us comprehend certain features of the biological world that would otherwise be difficult to explain. There are, for example, only a certain limited number of animal “types,” the Bauplane: invertebrates, vertebrates, insects, arachnids, etc., and species within each type share a remarkable degree of similarity (the finger bones in a bat wing and in the hand of a human, e.g.). Why is evolution so conservative? Mayr suggests that one possible explanation is that a major change in the underlying structure of an organism (for example, the addition of a new set of extremities) is usually so disruptive to the expression of the genotype as a whole that it is strongly selected against. “The same phenomenon is illustrated by the gill arches that still dominate the ontogeny of land-living vertebrates,” he notes. “It is obvious in all these cases that development is controlled by such a large number of interacting genes that the selection pressure to eliminate vestigial structures is less effective than the selection to maintain the efficiency of well established development pathways.”
The concept also helps explain the evidence of highly uneven rates of evolution (periods of relative stasis or gradual change followed by relatively rapid change). The unity of the genotype acts as a stabilizing force, resisting major evolutionary change, however this stability can be disrupted in certain situations such as the breakaway of “founder populations” (small populations that are separated from the population as a whole), which are confronted with new environmental conditions. [Mayr was really the first theorist to develop this concept, which he called “genetic revolutions,” though it has since become eclipsed by Gould and Eldridge’s more dubious theory of punctuated equilibria, which it is sometimes argued is in conflict with
For the moment I am simply throwing this concept out there, but hopefully I will develop these ideas in future posts. I think that it is highly significant that the lineage emerged first among Soviet scientists in the 1920s, pre-Lysenko and prior to the major phases of Stalinist repression. A serious examination of the work of these geneticists would be well worth the effort.